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Full donor chimerism by day 30 after allogeneic peripheral blood progenitor cell transplantation is associated with a low risk of relapse in pediatric patients with hematological malignancies.

作者信息

Lassaletta A, Ramírez M, Montero J M, González-Vicent M, Balas A, Madero L, Díaz M A

机构信息

Servicio de Oncohematología y Trasplante Hematopoyético, Hospital Infantil 'Niño Jesús', Madrid, Spain.

出版信息

Leukemia. 2005 Apr;19(4):504-6. doi: 10.1038/sj.leu.2403692.

DOI:10.1038/sj.leu.2403692
PMID:15729381
Abstract
摘要

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Full donor chimerism by day 30 after allogeneic peripheral blood progenitor cell transplantation is associated with a low risk of relapse in pediatric patients with hematological malignancies.异基因外周血祖细胞移植后30天时达到完全供者嵌合状态与血液系统恶性肿瘤患儿的低复发风险相关。
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Appl Clin Genet. 2025 Jul 24;18:131-146. doi: 10.2147/TACG.S520646. eCollection 2025.
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Validation of next-generation sequencing-based chimerism testing for accurate detection and monitoring of engraftment in hematopoietic stem cell transplantation.基于新一代测序的嵌合体检测在造血干细胞移植中准确检测和监测植入情况的验证
Front Genet. 2023 Oct 23;14:1282947. doi: 10.3389/fgene.2023.1282947. eCollection 2023.
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Is It Possible to Separate the Graft-Versus-Leukemia (GVL) Effect Against B Cell Acute Lymphoblastic Leukemia From Graft-Versus-Host Disease (GVHD) After Hematopoietic Cell Transplant?
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