Halota Waldemar, Pawłowska Małgorzata, Andrejczyn Michaił
Katedra i Klinika Chorób Zakaźnych Akademii Medycznej im. L.Rydygiera w Bydgoszczy.
Przegl Epidemiol. 2004;58(3):405-11.
Interferons play the main role in the treatment of chronic hepatitis C. In the clinical practice recombined forms of these cytokines dominate. Most recent obligatory standard of the treatment is combined therapy with pegylated interferon and ribavirin during 24 or 48 weeks dependent of HCV genotype. In some clinical cases, in which contraindications to these forms of drugs or adverse events appear, administration of natural interferon (alphaferon) is possible. Treatment with this form of interferon in these cases is safe and efficient.
干扰素在慢性丙型肝炎的治疗中起主要作用。在临床实践中，这些细胞因子的重组形式占主导地位。最新的强制性治疗标准是根据丙型肝炎病毒（HCV）基因型，采用聚乙二醇化干扰素和利巴韦林联合治疗24周或48周。在一些临床病例中，如果出现对这些药物形式的禁忌症或不良事件，可以使用天然干扰素（α干扰素）。在这些情况下，使用这种形式的干扰素进行治疗是安全有效的。
