Yajima Kazuhito, Shirai Yoshio, Fujita Nobuhiro, Sato Daisuke, Umezu Hajime, Hatakeyama Katsuyoshi
Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata City, 951-8510 Japan.
World J Surg Oncol. 2005 Feb 24;3(1):14. doi: 10.1186/1477-7819-3-14.
Subcutaneous leiomyosarcoma is a rare condition that accounts for 1% to 2% of all superficial soft tissue malignancies. Approximately 10% of cases arise in the trunk, although the extremities are the most commonly affected. CASE PRESENTATION: We report herein the case of a 31-year-old man with a subcutaneous leiomyosarcoma, measuring 124 x 105 mm, arising in the left inguinal region. A wide local excision (with a resection margin >/= 20 mm) was performed. Histological examination of the resected specimen revealed a leiomyosarcoma with high cellularity and two mitoses per 10 high-power fields. The patient remains well with no evidence of disease 5 years and 8 months after the operation. CONCLUSION: This is the first reported case of subcutaneous leiomyosarcoma arising in the inguinal region and also one of the largest tumors reported. The experience of this case and a review of the English-language literature (PubMed, National Library of Medicine, Bethesda, MD, USA) suggest that a resection margin of >/= 10 mm is recommended when excising this rare tumor.
皮下平滑肌肉瘤是一种罕见疾病，占所有浅表软组织恶性肿瘤的1%至2%。约10%的病例发生在躯干，不过四肢是最常受累部位。病例报告：我们在此报告一例31岁男性患者，其左侧腹股沟区出现一个大小为124×105毫米的皮下平滑肌肉瘤。进行了广泛局部切除（切除边缘≥20毫米）。对切除标本的组织学检查显示为一个细胞密度高且每10个高倍视野有两个核分裂象的平滑肌肉瘤。术后5年8个月，患者情况良好，无疾病迹象。结论：这是首例报告的腹股沟区皮下平滑肌肉瘤病例，也是所报告的最大肿瘤之一。该病例经验以及对英文文献（美国国立医学图书馆贝塞斯达分馆的PubMed）的回顾表明，切除这种罕见肿瘤时建议切除边缘≥10毫米。
