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[三阶段康复治疗对急性脑血管疾病的影响:一项前瞻性、随机、对照、多中心研究]

[Effects of three-stage rehabilitation treatment on acute cerebrovascular diseases: a prospective, randomized, controlled, multicenter study].

作者信息

Zhang Tong, Li Li-lin, Bi Sheng, Mei Yuan-wu, Xie Rui-man, Luo Zu-ming, Wang De-sheng, Wang Wei-zhi, Wang Ning-hua, Jia Jian-ping, Tan Lan, Ding Xin-sheng, Cui Li-ying, Wang De-xin, Hu Xue-qiang, Niu Zhu

机构信息

Neurorehabilitation Department of China Rehabilitation Research Center Affiliated to Capital University of Medical Sciences, Beijing 100068, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2004 Dec 2;84(23):1948-54.

Abstract

OBJECTIVE

To evaluate the effect of tertiary rehabilitation treatment on acute cerebrovascular diseases.

METHODS

Fifteen tertiary rehabilitation networks were set up throughout the country. 1078 patients with acute cerebrovascular diseases were randomly divided into 2 groups: rehabilitation group and control group, out of which 19 patients died, 157 dropped out, and 7 successive evaluations were completed in 902 patients that. 439 of the remaining 902 patients in the rehabilitation group, 266 males and 173 females, aged 61 +/- 11, 278 cases with cerebral infarction and 161 with cerebral hemorrhage, received routine treatment and early rehabilitation for 28 days in the ward of neurology, and then went home and received community rehabilitation for 6 months or underwent specialized reinforcement training for 2 months and after that went home and received community rehabilitation for 4 months. The 463 patients in the control group, 281 males and 182 females, aged 60 +/- 11, 291 of which with cerebral infarction and 172 with cerebral hemorrhage, received only routine treatment and early rehabilitation for 28 days in the ward of neurology, and then went home to conduct rehabilitation training by themselves or their family members for 6 months. Evaluation was conducted 7 times, with National Institutes of Health Stroke Scale (NIHSS), Fugl-Meyer motor function scale, Barthel index, SF-36 scale, Lowenstein occupational therapy cognitive assessment (LOTCA), Westen aphasia battery, Hamilton depression scale, and modified Ashworth spasm scale, one week after the onset and by the ends of 1, 2, 3, 4, 5, and 6 months after the onset respectively.

RESULTS

The scores of clinical neurological impairment, Fugl-Meyer scores, SF-36 scores, incidence of PSD, and modified Ashworth scores (for upper and lower limbs) were lower, and LOTCA scores and Barthel indexes were higher at different time points in the rehabilitation group than in the control group; and the differences were statistically significant since the 2nd month after the onset. By the end of the 6th month, the patients of the rehabilitation group basically re-achieved the ability of self-care in daily activities with a Barthel index of 84 +/- 33. The patients of the control group also recovered to a certain degree, however, to a smaller extent in comparison with the rehabilitation group.

CONCLUSION

Tertiary rehabilitation treatment of cerebrovascular diseases is effective in improving motor function, ability of daily living activities, and quality of life and reducing the incidence rates of secondary complications.

摘要

目的

评估三级康复治疗对急性脑血管疾病的效果。

方法

在全国建立了15个三级康复网络。1078例急性脑血管疾病患者被随机分为两组:康复组和对照组,其中19例死亡,157例退出,902例患者完成了7次连续评估。康复组剩余902例患者中的439例,男性266例,女性173例,年龄61±11岁,脑梗死278例,脑出血161例,在神经内科病房接受常规治疗和早期康复28天,然后回家接受6个月的社区康复或接受2个月的专门强化训练,之后回家接受4个月的社区康复。对照组的463例患者,男性281例,女性182例,年龄60±11岁,其中脑梗死291例,脑出血172例,仅在神经内科病房接受常规治疗和早期康复28天,然后回家由自己或家人进行6个月的康复训练。分别在发病后1周及发病后1、2、3、4、5、6个月结束时进行7次评估,评估指标包括美国国立卫生研究院卒中量表(NIHSS)、Fugl-Meyer运动功能量表、Barthel指数、SF-36量表、洛温斯坦认知作业疗法评估(LOTCA)、西方失语成套测验、汉密尔顿抑郁量表和改良Ashworth痉挛量表。

结果

康复组在不同时间点的临床神经功能缺损评分、Fugl-Meyer评分、SF-36评分、PSD发生率和改良Ashworth评分(上肢和下肢)均低于对照组,LOTCA评分和Barthel指数高于对照组;自发病后第2个月起差异有统计学意义。到第6个月末,康复组患者基本重新获得日常生活自理能力,Barthel指数为84±33。对照组患者也有一定程度的恢复,但与康复组相比恢复程度较小。

结论

脑血管疾病的三级康复治疗在改善运动功能、日常生活活动能力和生活质量以及降低继发并发症发生率方面是有效的。

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