Lucena Rita, Fonseca Natascha, Nunes Luciana, Cardoso Adriana, Goes Julieta, Correia Maria Cecília, Cardoso Eduardo, Queirós Fernanda, Anjos Luzia Poliana, Vila-Nova Camila, Melo Ailton
Division of Neurology and Epidemiology (DINEP)-Federal University of Bahia, Canela CEP:40.110-170 Salvador-Bahia, Brazil.
Pediatr Neurol. 2005 Mar;32(3):180-3. doi: 10.1016/j.pediatrneurol.2004.09.016.
Predictor variables of intra-hospital lethality among infants with pyogenic meningitis due to Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae were identified using data from a follow-up study of infants with bacterial meningitis. The infants who were admitted to Couto Maia Hospital from March 1, 1997 to December 31, 1997 presenting with symptoms of bacterial meningitis were identified and included in a database. An analysis of the clinical and laboratory information was performed using EPI info 6.01b and SPSS 6.1 statistical programs. The total mortality rate was 17.1%, and the majority of deaths occurred within 48 hours of hospitalization. Factors associated most frequently with poor outcome included absence of respiratory infection, high cerebrospinal fluid protein, and compromised cranial nerves. Early identification of major risk groups is important to adopt measures to improve prognosis.
利用一项针对细菌性脑膜炎患儿的随访研究数据，确定了由脑膜炎奈瑟菌、流感嗜血杆菌和肺炎链球菌引起的化脓性脑膜炎患儿院内致死率的预测变量。确定了1997年3月1日至1997年12月31日期间因细菌性脑膜炎症状入住库托·马亚医院的婴儿，并将其纳入数据库。使用EPI info 6.01b和SPSS 6.1统计程序对临床和实验室信息进行分析。总死亡率为17.1%，大多数死亡发生在住院48小时内。与不良预后最常相关的因素包括无呼吸道感染、脑脊液蛋白高和颅神经受损。早期识别主要风险组对于采取改善预后的措施很重要。
