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对三个社区国民保健服务信托机构中因牙科全身麻醉而转诊的儿童使用治疗性抗生素的情况进行调查。

An investigation of therapeutic antibiotic prescribing for children referred for dental general anaesthesia in three community national health service trusts.

作者信息

Harte H, Palmer N O A, Martin M V

机构信息

North Liverpool P.C.T., 3 Glendyke Road, Liverpool L18 6JR, England, UK.

出版信息

Br Dent J. 2005 Feb 26;198(4):227-31, discussion 215. doi: 10.1038/sj.bdj.4812091.

Abstract

OBJECTIVE

To investigate antibiotic prescribing for paediatric dental patients requiring general anaesthesia.

DESIGN

A prospective clinical study of children referred for dental treatment under general anaesthesia.

METHOD

Information was collected by way of a two-stage questionnaire for children attending three community NHS trusts for dental extractions under general anaesthesia between July 2001 and January 2003.

RESULTS

A total of 360 questionnaires were analysed. There was wide variation in the waiting times (0-278 days) between referral and treatment under general anaesthesia. Most children (53%) attended with dento-alveolar abscess, 46% with caries only and 1% for orthodontic extractions. Antibiotics were prescribed to 52% of patients with an abscess and 32% with caries only. Only 16% of patients presented with moderate to severe pain, 5.5% with diffuse swelling and 12% with a raised temperature. Antibiotics were prescribed for patients with diffuse swelling (63%) and raised temperature (50%) but also for patients with pain only (39%) and localised swelling (52%). Amoxicillin was the most frequently prescribed antibiotic (82%), with wide variation in all antibiotic regimens.

CONCLUSION

This study provides evidence of inappropriate prescribing of antibiotics to children referred for treatment under general anaesthesia with wide variations in the regimens employed. There was no conclusive evidence that long waiting times for definitive treatment influenced antibiotic prescribing. In some areas the delay for definitive treatment for this group of vulnerable patients was unacceptably long.

摘要

目的

调查需要全身麻醉的儿科牙科患者的抗生素处方情况。

设计

对接受全身麻醉下牙科治疗的儿童进行的前瞻性临床研究。

方法

通过两阶段问卷收集2001年7月至2003年1月期间在三个国民保健服务社区信托机构接受全身麻醉下拔牙治疗的儿童的信息。

结果

共分析了360份问卷。转诊至全身麻醉治疗之间的等待时间差异很大(0 - 278天)。大多数儿童(53%)因牙槽脓肿就诊,46%仅因龋齿就诊,1%因正畸拔牙就诊。52%患有脓肿的患者和32%仅患有龋齿的患者使用了抗生素。只有16%的患者出现中度至重度疼痛,5.5%出现弥漫性肿胀,12%体温升高。抗生素被用于弥漫性肿胀(63%)和体温升高(50%)的患者,但也用于仅疼痛(39%)和局部肿胀(52%)的患者。阿莫西林是最常开具的抗生素(82%),所有抗生素治疗方案差异很大。

结论

本研究提供了证据,表明对接受全身麻醉治疗的儿童存在不适当的抗生素处方,所采用的治疗方案差异很大。没有确凿证据表明确定性治疗的长时间等待会影响抗生素处方。在某些地区,这组弱势患者的确定性治疗延迟时间长得令人无法接受。

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