Duarte Helena, Ormonde Lucindo, Lima Figueiredo
Serviço de Anestesiologia, Hospital de Santa Maria, Lisboa.
Rev Port Cir Cardiotorac Vasc. 2004 Oct-Dec;11(4):213-6.
Major vascular surgery patients are at great risk of renal failure. Several pharmacological and non pharmacological strategies have been developed to prevent renal failure in those patients. Renal doses of dopamine were used, based on its beneficial effects on renal function, in animals and healthy individuals. However, major vascular surgery patients are often critically ill, with diverse pathophysiological conditions and they cannot be easily compared to healthy individuals. There are, nowadays, enough scientific evidence demonstrating that renal doses of dopamine do not play a significant protective role of renal function in these critically ill patients.
接受大血管手术的患者面临肾衰竭的高风险。已经开发了几种药物和非药物策略来预防这些患者的肾衰竭。基于多巴胺对肾功能的有益作用，曾在动物和健康个体中使用肾脏剂量的多巴胺。然而，接受大血管手术的患者通常病情危急，存在多种病理生理状况，难以与健康个体进行简单比较。如今，有足够的科学证据表明，肾脏剂量的多巴胺在这些重症患者中对肾功能并无显著的保护作用。
