Sanz Santaeufemia F J, Ramos Amador J T, Giangaspro E, Sánchez Granados J M, Palenque E, González Tomé M I
Centro de Salud Baviera, Area 2, Instituto Madrileño de la Salud, Madrid, Spain.
An Pediatr (Barc). 2005 Mar;62(3):280-5. doi: 10.1157/13071845.
In recent years, lymphadenitis caused by atypical mycobacteria (also called nontuberculous mycobacteria [NTMB] or, more recently, environmental) have played a significant role in the differential diagnosis of adenitis in non-immunocompromised children.
To describe the clinical and pathological findings in childhood NTMB adenitis and study the possible usefulness of antimicrobial therapy in addition to surgery.
We present eight cases of neck lymphadenitis occurring over a 5-year period. All of the children received combined chemotherapy, and six also underwent surgery. Of the two remaining patients, the parents of one child refused surgery and a watchful approach was adopted in the other.
Complete clinical recovery was achieved in all patients except one who did not undergo surgery.
Prolonged administration of two antibiotics (of which one must be clarithromycin) in addition to surgery was well-tolerated and could be useful in patients with NTMB neck lymphadenitis.
近年来，非典型分枝杆菌（也称为非结核分枝杆菌[NTMB]，或最近称为环境分枝杆菌）引起的淋巴结炎在非免疫功能低下儿童腺炎的鉴别诊断中发挥了重要作用。
描述儿童NTMB腺炎的临床和病理表现，并研究除手术外抗菌治疗的可能效用。
我们呈现了5年内发生的8例颈部淋巴结炎病例。所有儿童均接受了联合化疗，其中6例还接受了手术。在其余2例患者中，1例患儿的父母拒绝手术，另一例则采取了观察等待的方法。
除1例未接受手术的患者外，所有患者均实现了临床完全康复。
除手术外，长期使用两种抗生素（其中一种必须是克拉霉素）耐受性良好，对NTMB颈部淋巴结炎患者可能有用。
