Woto-Gaye Gisèle, Kasse Abdoul Aziz, Dieye Yakou, Toure Papa, Demba Ndiaye Papa
Laboratoire d'Anatomie et de Cytologie Pathologiques, Faculté de Médecine et de Pharmacie, U.C.A.D., Dakar, Sénégal.
Ann Pathol. 2004 Oct;24(5):432-5; quiz 393. doi: 10.1016/s0242-6498(04)93999-5.
Secretory carcinoma or juvenile carcinoma of the breast is a very rare tumor of male adults. Generally, it has a good prognosis after locoregional treatment. The authors report an observation of a secretory carcinoma occurring in a 20 year old man. The lesion presented as a voluminous tumor 12 cm in diameter with 3 positive lymph nodes; it was treated by mastectomy and axillary dissection. Tumor developed in a few months, with visceral metastasis and fatal issue. The cytological, histological and immuno-histochemical features necessary to the diagnosis are described. The rapid development of this case of secretory carcinoma is unusual. This leads the authors to propose the use of an additional treatment for adult secretory breast carcinoma with more than 3 positive lymph nodes.