Davies R Justin, Miller Richard, Coleman Nicholas
Medical Research Council Cancer Cell Unit, Hutchison/MRC Research Centre, Hills Road, Cambridge, CB2 2XZ, UK.
Nat Rev Cancer. 2005 Mar;5(3):199-209. doi: 10.1038/nrc1569.
Colorectal cancer is common. As many patients present with advanced disease, an effective screening test would have substantial clinical benefits. Recent progress in understanding the biology of colorectal cancer (and of cancer cells in general) has led to possible new approaches to screening. In particular, there are prospects of developing tests based on analysis of stool, which promise improved accuracy, safety, affordability and patient compliance.
结直肠癌很常见。由于许多患者就诊时已处于疾病晚期，一种有效的筛查测试将具有重大的临床益处。最近在理解结直肠癌（以及一般癌细胞）生物学方面取得的进展，带来了可能的新筛查方法。特别是，基于粪便分析开发测试具有前景，有望提高准确性、安全性、可承受性和患者依从性。
