Hoyt D J, Lettinga J W, Leopold K A, Fisher S R
Department of Surgery, Duke University Medical Center, Durham, NC 27710.
Laryngoscope. 1992 May;102(5):477-80. doi: 10.1288/00005537-199205000-00001.
Twenty-five patients with squamous cell carcinoma of the head and neck who received radiation therapy as their only form of treatment underwent a computer-assisted voice analysis before, and 6 months following treatment. Those with early laryngeal tumors had a significant improvement in intelligibility (P = .07), percent of sound voiced (P = .04), and sound perturbation. Those with nonlaryngeal tumors had no change in any measured parameters. Head and neck radiation therapy can significantly improve the voice quality of patients with laryngeal tumors, while having a minimal effect on the voice quality of those with nonlaryngeal tumors.
25例仅接受放射治疗的头颈部鳞状细胞癌患者在治疗前及治疗后6个月接受了计算机辅助语音分析。早期喉肿瘤患者在可懂度（P = 0.07）、浊音百分比（P = 0.04）和声音扰动方面有显著改善。非喉肿瘤患者的任何测量参数均无变化。头颈部放射治疗可显著改善喉肿瘤患者的语音质量，而对非喉肿瘤患者的语音质量影响最小。
