Oancea I
Klin Monbl Augenheilkd. 1975 Oct;167(4):618-22.
In 27 patients with non-compensated or medically compensated chronic simple glaucoma, the I.O.P. was measured after the administration of two tablets of beta-isoket (which contain 5 mg isosorbiddinitrate and 40 mg bupranolol). In none of the 54 eyes was the I.O.P. higher after administration of the drug. On the contrary, the I.O.P. was siginificantly or highly significantly reduced for more than 2 hours, probably because of the beta-receptor-blocking component of the preparation.
在27例未代偿或药物代偿性慢性单纯性青光眼患者中,给予两片倍他乐克(每片含5毫克硝酸异山梨酯和40毫克布普萘洛尔)后测量眼压。在54只眼中,用药后眼压均未升高。相反,眼压显著或极显著降低超过2小时,这可能是由于该制剂中的β受体阻滞剂成分所致。