Arboix A, García-Eroles L, Massons J, Oliveres M, Comes E, Targa C
Cerebrovascular Division, Department of Neurology, Hospital del Sagrat Cor, Barcelona, Spain.
Acta Neurol Scand. 2005 Apr;111(4):253-7. doi: 10.1111/j.1600-0404.2005.00353.x.
To compare the characteristics of lacunar stroke (LS) in patients with and without intermittent claudication.
Data of 484 consecutive patients with LS were collected from a prospective hospital-based stroke registry in which 2500 patients are included.
Of the 142 patients with ischemic stroke and intermittent claudication, 39 (27.5%) had LS (8% of all lacunes). In the multivariate analysis, small centrum ovale topography (odds ratio 7.35), carotid stenosis >50% (odds ratio 3.17), and absence of limitation at discharge (odds ratio 2.01) were independent variables significantly associated with LS in patients with intermittent claudication.
Only 8% of patients with LS had intermittent claudication. The short-term prognosis is good with a spontaneous early neurological recovery at discharge in 51.3% of patients. LS patients with intermittent claudication showed a striking similarity in risk factors and clinical syndromes in comparison with the LS patients without intermittent claudication.
比较有间歇性跛行和无间歇性跛行的腔隙性卒中(LS)患者的特征。
从一个前瞻性的基于医院的卒中登记处收集了484例连续的LS患者的数据,该登记处共纳入了2500例患者。
在142例患有缺血性卒中和间歇性跛行的患者中,39例(27.5%)患有LS(占所有腔隙性梗死的8%)。在多变量分析中,小卵圆中心部位(比值比7.35)、颈动脉狭窄>50%(比值比3.17)以及出院时无功能受限(比值比2.01)是与间歇性跛行患者的LS显著相关的独立变量。
只有8%的LS患者有间歇性跛行。短期预后良好,51.3%的患者出院时神经功能自发早期恢复。与无间歇性跛行的LS患者相比,有间歇性跛行的LS患者在危险因素和临床综合征方面表现出惊人的相似性。