扩大DNA记忆的潜力：放大嵌套引物分子记忆实验操作的有效性。

Potential for enlarging DNA memory: the validity of experimental operations of scaled-up nested primer molecular memory.

作者信息

Kashiwamura Satoshi, Yamamoto Masahito, Kameda Atsushi, Shiba Toshikazu, Ohuchi Azuma

机构信息

Graduate School of Engineering, Hokkaido University, North 13, West 8, Kita-ku, Sapporo 060-8628, Japan.

出版信息

Biosystems. 2005 Apr;80(1):99-112. doi: 10.1016/j.biosystems.2004.10.007. Epub 2004 Dec 8.

DOI:10.1016/j.biosystems.2004.10.007

PMID:15740839

Abstract

DNA is an attractive memory unit because of its immense information density. Here, we describe a memory model made of DNA, called Nested Primer Molecular Memory (NPMM). NPMM consists of many DNA strands, and each DNA strand consists of two areas: a data area and a data address area. When the address of target data is specified, only the target data can be extracted from NPMM. In this paper, we evaluate the validity of the basic operations of NPMM and then discuss the feasibility of scaled-up NPMM through some laboratory experiments. In the latter, we deal with scaled-up NPMM simulated by the Concentration Scaling method.

摘要

由于其巨大的信息密度，DNA是一种颇具吸引力的存储单元。在此，我们描述一种由DNA构成的存储模型，称为嵌套引物分子记忆（NPMM）。NPMM由许多DNA链组成，每条DNA链由两个区域构成：一个数据区域和一个数据地址区域。当指定目标数据的地址时，仅能从NPMM中提取目标数据。在本文中，我们评估NPMM基本操作的有效性，然后通过一些实验室实验讨论扩大规模的NPMM的可行性。在后者中，我们处理通过浓度缩放方法模拟的扩大规模的NPMM。