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[诊断链球菌性咽炎的临床及实验室方法的比较分析]

[Comparative analysis of clinical and laboratory methods for diagnosing streptococcal sore throat].

作者信息

dos Santos Ana Gabriela P, Berezin Eitan N

机构信息

Faculdade de Ciências Médicas, Santa Casa de São Paulo, SP.

出版信息

J Pediatr (Rio J). 2005 Jan-Feb;81(1):23-8.

Abstract

OBJECTIVES

Diagnosis and correct treatment of group A streptococcal sore throat is important particularly to prevent non-suppurative sequelae. Clinical findings continue to be used to differentiate streptococcal infection from viral sore throat. The American Academy of Pediatrics recommends that streptococcal sore throat diagnosis should always be performed by microbiological identification methods. The aim of this study is to evaluate the accuracy of clinical diagnosis in comparison with culture and rapid test.

METHODS

Children aged 2 to 13 years who had received a clinical diagnosis of sore throat and sought treatment at the pediatric emergency unit of São Paulo Santa Casa were evaluated and those with clinical signs or viral infection were excluded. Clinical findings were recorded and swabs were taken for group A Streptococcus cultures and a Streptococcus rapid test.

RESULTS

The culture was positive in 96 (24.4%) of the 376 children evaluated. The presence of petechiae, purulent exudate and painful tonsils were more likely to occur in children with positive streptococcus cultures, however they exhibited low diagnostic accuracy. The doctors' subjective evaluation failed to identify 21% of positive cases and antibiotics were prescribed in 47% of negative cases, compared with 3 and 6%, respectively, for the rapid test.

CONCLUSIONS

A microbiologic method is necessary for the correct prescription of antibiotics in children with streptococcal sore throat.

摘要

目的

A组链球菌性咽炎的诊断和正确治疗尤为重要,特别是为了预防非化脓性后遗症。临床症状仍被用于区分链球菌感染和病毒性咽炎。美国儿科学会建议,链球菌性咽炎的诊断应始终通过微生物鉴定方法进行。本研究的目的是评估临床诊断与培养及快速检测相比的准确性。

方法

对在圣保罗圣卡塔琳娜儿科急诊室接受过咽炎临床诊断并寻求治疗的2至13岁儿童进行评估,排除有临床体征或病毒感染的儿童。记录临床症状,并采集拭子进行A组链球菌培养和链球菌快速检测。

结果

在376名接受评估的儿童中,96名(24.4%)培养结果呈阳性。瘀点、脓性渗出物和扁桃体疼痛在链球菌培养阳性的儿童中更易出现,然而它们的诊断准确性较低。医生的主观评估未能识别出21%的阳性病例,在阴性病例中分别有47%的患儿被开了抗生素,而快速检测的这一比例分别为3%和6%。

结论

对于患有链球菌性咽炎的儿童,正确开具抗生素需要采用微生物学方法。

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