Recober Ana, Geweke Lynne O
Department of Neurology, Division of Head and Facial Pain, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 2 RCP, Iowa City, IA 52242, USA.
Curr Neurol Neurosci Rep. 2005 Mar;5(2):93-8. doi: 10.1007/s11910-005-0005-4.
Migraine is a common disorder that is disproportionately prevalent in women, especially during the reproductive years. Hormonal changes may play a role in the etiology of migraine, as many women note that their migraine attacks occur in temporal relationship with their menses. The Headache Classification Subcommittee of the International Headache Society has recently defined menstrual and menstrually related migraine. We review the most relevant and recent literature on menstrual migraine, with a special focus on pathophysiology and therapy. Although the pathogenesis of menstrual and menstrually related migraine is not well understood, estrogen withdrawal seems to play an important role as a trigger for menstrual migraine attacks. The therapeutic approach also may differ from the treatment of nonmenstrual migraine. Some patients do not require prophylaxis when they can abort their attacks effectively, whereas others may benefit from perimenstrual prophylaxis or standard migraine prophylaxis.
偏头痛是一种常见疾病，在女性中发病率过高，尤其是在生育年龄段。激素变化可能在偏头痛的病因中起作用，因为许多女性注意到她们的偏头痛发作与月经在时间上相关。国际头痛协会头痛分类小组委员会最近对经期偏头痛和与月经相关的偏头痛进行了定义。我们回顾了关于经期偏头痛的最相关和最新文献，特别关注其病理生理学和治疗方法。尽管经期偏头痛和与月经相关的偏头痛的发病机制尚未完全了解，但雌激素撤退似乎作为经期偏头痛发作的触发因素起着重要作用。治疗方法也可能与非经期偏头痛的治疗不同。一些患者在能够有效终止发作时不需要预防性治疗，而另一些患者可能从经前期预防或标准偏头痛预防中获益。
