色觉和非色觉视觉通路的差异老化：行为学与电生理学研究

Differential aging of chromatic and achromatic visual pathways: behavior and electrophysiology.

作者信息

Page Jonathan W, Crognale Michael A

机构信息

Department of Psychology, University of Nevada, Reno, NV 89557, USA.

出版信息

Vision Res. 2005 May;45(11):1481-9. doi: 10.1016/j.visres.2004.09.041.

DOI:10.1016/j.visres.2004.09.041

PMID:15743617

Abstract

Aging of visual pathways was measured psychophysically and physiologically in subjects aged 20-89 years. Contrast thresholds for the chromatic pathways increased with age, but there were no significant changes for thresholds of the achromatic pathway at low spatial frequencies. For visual evoked potential (VEP) responses, again only the chromatic pathways were significantly affected by age. Age-related changes in chromatic responses were not apparent when stimuli were adjusted by age-related contrast thresholds. This suggests that the chromatic and achromatic visual pathways age differently and that the VEP accurately and objectively reflects behavioral changes with age.

摘要

对年龄在20至89岁的受试者的视觉通路老化情况进行了心理物理学和生理学测量。色觉通路的对比度阈值随年龄增长而增加，但在低空间频率下，无色觉通路的阈值没有显著变化。对于视觉诱发电位（VEP）反应，同样只有色觉通路受到年龄的显著影响。当根据与年龄相关的对比度阈值调整刺激时，色觉反应中与年龄相关的变化并不明显。这表明色觉和无色觉视觉通路的老化方式不同，并且VEP能够准确、客观地反映随年龄增长的行为变化。