青光眼药物与房水动力学
Glaucoma medication and aqueous humor dynamics.
作者信息
Crowston Jonathan G, Weinreb Robert N
机构信息
Hamilton Glaucoma Center, University of California San Diego, La Jolla, California 92093-0946, USA.
出版信息
Curr Opin Ophthalmol. 2005 Apr;16(2):94-100. doi: 10.1097/01.icu.0000156136.20570.eb.
PURPOSE OF REVIEW
This review evaluates current concepts regarding the effects of glaucoma medication on aqueous humor dynamics and the impact of this on intraocular pressure control and drug selection in clinical practice.
RECENT FINDINGS
Calculations based on the Friedenwald and Goldmann equations have predicted that glaucoma medications that increase pressure-sensitive aqueous outflow will dampen intraocular pressure spikes and therefore may be advantageous over drugs that do not increase outflow facility.
SUMMARY
Further experimental research is required to verify the influence of increased outflow facility on intraocular pressure fluctuation and the effect of this on glaucoma progression.
综述目的
本综述评估了关于青光眼药物对房水动力学的影响以及这在临床实践中对眼压控制和药物选择的影响的当前概念。
最新发现
基于弗里登瓦尔德和戈德曼方程的计算预测，增加对压力敏感的房水流出的青光眼药物将抑制眼压峰值，因此可能比不增加流出率的药物更具优势。
总结
需要进一步的实验研究来验证增加流出率对眼压波动的影响以及这对青光眼进展的作用。
Zotero 插件