Jefferson James W
Madison Institute of Medicine, Inc., Madison, WI 53717, USA.
CNS Spectr. 2005 Mar;10(3):224-32. doi: 10.1017/s1092852900010063.
Following the introduction of lamotrigine in 1994 as a treatment for epilepsy in the United States, the drug has seen progressively greater application in psychiatry, particularly as a treatment for bipolar disorder. This review critically evaluates the support for lamotrigine use across a broad range of psychiatric disorders as well as discuss its pharmacology, side-effect profile, and interactions with other medications.
1994年拉莫三嗪在美国被引入用于治疗癫痫后,该药物在精神病学领域的应用越来越广泛,尤其是作为双相情感障碍的一种治疗方法。这篇综述批判性地评估了拉莫三嗪在广泛的精神疾病中的应用依据,并讨论了其药理学、副作用概况以及与其他药物的相互作用。