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日光性荨麻疹和卟啉病。

Solar urticaria and porphyrias.

作者信息

Palma-Carlos A G, Palma-Carlos M L

机构信息

Immunoallergology Department, Santa Maria Hospital, Lisbon, Portugal.

出版信息

Eur Ann Allergy Clin Immunol. 2005 Jan;37(1):17-20.

Abstract

The importance of disturbances of porphyrin metabolism in solar urticaria is discussed. 15 cases of porphyrias with sun sensitivity are presented comprising 5 cases of erythropoietic protoporhyria, 8 cases of coproporphyria hereditaria and 2 cases of porphyria variegata, 9 out of these 10 patients presented neuroabdominal symptoms and in 4 cases contraceptive pills have triggered the disease. Due to the risk of severe forms of disease sometimes drugs induced porphyrias must be considered in all cases of solar urticaria and a correct laboratory study done in the suspected cases.

摘要

本文讨论了卟啉代谢紊乱在日光性荨麻疹中的重要性。报告了15例对日光敏感的卟啉病患者,其中包括5例红细胞生成性原卟啉病、8例遗传性粪卟啉病和2例混合型卟啉病。这15例患者中有10例出现了神经腹部症状,4例患者的病情由避孕药诱发。由于存在病情严重的风险,对于所有日光性荨麻疹患者,均应考虑药物性卟啉病的可能性,并对疑似病例进行正确的实验室检查。

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