Felix Marcelo M, Castro Luiz H M, Maia Antonio Carlos Martins, da Rocha Antonio J
Department of Radiology, Hospital das Clínicas-Universidade de São Paulo and Section of Radiology, Fleury Centro de Medicina Diagnostica, Brazil.
J Neuroimaging. 2005 Apr;15(2):203-5. doi: 10.1177/1051228404272878.
Transient global amnesia is a benign syndrome of sudden-onset alteration of behavior with temporary dysfunction of anterograde and recent retrograde memory. Its neural substrates remain uncertain. Possible causes include ischemia, migraine, and epilepsy. The authors report a case of a 62-year-old man with a transient attack of memory disturbance, suggestive of transient global amnesia, in which magnetic resonance imaging performed 48 hours after onset showed left mesial temporal lobe signal changes on diffusion-weighted imaging and fluid-attenuated inversion recovery images. The findings and a literature review lend further support to the ischemic pathogenesis of transient global amnesia as a possible etiology, and underscore the role of diffusion-weighted imaging in the diagnosis of this condition.
短暂性全面性遗忘症是一种行为突然改变的良性综合征，伴有顺行性和近期逆行性记忆的暂时功能障碍。其神经基质尚不确定。可能的病因包括缺血、偏头痛和癫痫。作者报告了一例62岁男性，出现短暂性记忆障碍发作，提示短暂性全面性遗忘症，发病后48小时进行的磁共振成像显示，扩散加权成像和液体衰减反转恢复图像上左侧颞叶内侧有信号变化。这些发现以及文献综述进一步支持了短暂性全面性遗忘症的缺血性发病机制作为一种可能病因，并强调了扩散加权成像在该疾病诊断中的作用。
