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猫抓病:耳鼻喉科表现及处理

Cat-scratch disease: Otolaryngologic manifestations and management.

作者信息

Ridder Gerd Jürgen, Boedeker Carsten Christof, Technau-Ihling Katja, Sander Anna

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, University of Freiburg, Freiburg, Germany.

出版信息

Otolaryngol Head Neck Surg. 2005 Mar;132(3):353-8. doi: 10.1016/j.otohns.2004.09.019.

Abstract

OBJECTIVE

The bacteria Bartonella henselae has been known as the principal causative agent of cat-scratch disease (CSD) since 1992. It is an important cause of infectious lymphadenopathies in the head and neck. Nevertheless, CSD often remains unrecognized in cases of cervicofacial lymph node enlargement.

STUDY DESIGN

Between January 1997 and May 2003, we conducted a prospective clinical study including 721 patients with primarily unclear masses in the head and neck.

RESULTS

CSD was diagnosed by serology and molecular investigations in 99 patients (13.7%; median age 33 years). Cervicofacial lymphadenopathy was the most common manifestation. Atypical manifestation of CSD including Parinaud's oculoglandular syndrome, swelling of the parotid gland and erythema nodosum were diagnosed in 8.1%, 8.1%, and 2.0% of cases, respectively.

CONCLUSIONS

Our results demonstrate that CSD is a major cause of enlarged cervicofacial lymph nodes and should therefore be included in the differential diagnosis of lymphadenopathy in the head and neck region.

摘要

目的

自1992年以来,亨氏巴尔通体一直被认为是猫抓病(CSD)的主要病原体。它是头颈部感染性淋巴结病的重要病因。然而,在面颈部淋巴结肿大的病例中,CSD常常未被识别。

研究设计

在1997年1月至2003年5月期间,我们进行了一项前瞻性临床研究,纳入了721例头颈部主要肿块性质不明的患者。

结果

通过血清学和分子检测,在99例患者(13.7%;中位年龄33岁)中诊断出CSD。面颈部淋巴结病是最常见的表现。CSD的非典型表现包括帕里诺眼腺综合征、腮腺肿大和结节性红斑,分别在病例中的占比为8.1%、8.1%和2.0%。

结论

我们的结果表明,CSD是面颈部淋巴结肿大的主要原因,因此应纳入头颈部淋巴结病的鉴别诊断。

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