[通过植入聚氯乙烯摄像头的大鼠深部伤口模型对伤口愈合过程进行综合评估]

[Complex evaluation of wound healing process by a deep wound rat model with implanted polychlorvinyl camera].

作者信息

Galibin O V, Voronkina I V, Prokopchuk S N, Protasov M V, Solov'eva M A, Pinaev G P

出版信息

Tsitologiia. 2004;46(12):1073-9.

Abstract

A simultaneous study of wound proteolytic activity and morphological picture of the first stages of wound healing on rat deep wound model has been shown. The process of wound healing can be evaluated by dynamics of matrix metalloproteinase activities in wound fluid. Changes in activities of different matrix metalloproteinases correlate with different stages of healing. Implantation of polychlorvinyl camera in the wound makes it possible to obtain the volume of wound fluid sufficient for a complex evaluation of healing at the initial stages of wound process.

摘要

在大鼠深度伤口模型上，对伤口蛋白水解活性和伤口愈合初期形态学图像进行了同步研究。伤口愈合过程可通过伤口液中基质金属蛋白酶活性的动态变化来评估。不同基质金属蛋白酶活性的变化与愈合的不同阶段相关。在伤口中植入聚氯乙烯腔室，能够获取足够量的伤口液，以便对伤口愈合初期进行综合评估。