Imran Mudassar, Jones Don, Smith Hal
Department of Mathematics and Statistics, Arizona State University, Tempe, AZ 85287, USA.
Math Biosci. 2005 Feb;193(2):183-204. doi: 10.1016/j.mbs.2004.10.008.
Can a conjugative plasmid encoding enhanced biofilm forming abilities for its bacterial host facilitate the persistence of the plasmid in a bacterial population despite conferring diminished growth rate and segregative plasmid loss on its bearers? We construct a mathematical model in a chemostat and in a plug flow environment to answer this question. Explicit conditions for an affirmative answer are derived. Numerical simulations support the conclusion.
一个为其细菌宿主编码增强生物膜形成能力的接合质粒，尽管会使其携带者的生长速率降低并导致质粒发生分离性丢失，但它能否促进该质粒在细菌群体中的持续存在呢？我们构建了一个在恒化器和活塞流环境中的数学模型来回答这个问题。得出了肯定答案的明确条件。数值模拟支持这一结论。
