Skopková J, Schück O, Cort J H
Physiol Bohemoslov. 1979;28(3):201-8.
Brattleboro rats with diabetes insipidus (DI) will, if no other fluid is offered, drink their own previous day's urine. Such oral urine-recycling, where normal elimination is effective only in 15%, does not result in clinical or laboratory signs of uraemia even after 20 days. Serum electrolytes and creatinine remained normal, serum osmolarity and urea were slightly raised, but none of the parameters measured could be classified as uraemic. Extrarenal excretion of electrolytes increased. It is suggested that when the excreted load is represented to the organism from the gut lumen (as opposed to re-presentation into the peritoneal cavity or cessation of renal function) the gut wall serves a protective function by not reabsorbing significant portions of both the inorganic and organic loads in the urine. More detailed analysis will be required to establish this suggestion.
患有尿崩症（DI）的布拉德福德大鼠，如果没有提供其他液体，会饮用自己前一天的尿液。这种口服尿液再循环情况，正常排泄仅15%有效，即使在20天后也不会导致尿毒症的临床或实验室体征。血清电解质和肌酐保持正常，血清渗透压和尿素略有升高，但所测参数均不能归类为尿毒症指标。电解质的肾外排泄增加。有人提出，当从肠腔向机体呈现排泄负荷时（与重新注入腹腔或肾功能停止相反），肠壁通过不重吸收尿液中大部分无机和有机负荷起到保护作用。需要更详细的分析来证实这一观点。
