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门诊环境下无需局部麻醉或静脉镇静的Thermachoice子宫内膜消融术:一项前瞻性队列研究。

Thermachoice endometrial ablation in the outpatient setting, without local anesthesia or intravenous sedation: a prospective cohort study.

作者信息

Marsh Fiona, Thewlis Jenny, Duffy Sean

机构信息

Academic Department of Obstetrics and Gynaecology, St. James's University Hospital, Leeds, United Kingdom.

出版信息

Fertil Steril. 2005 Mar;83(3):715-20. doi: 10.1016/j.fertnstert.2004.08.030.

DOI:10.1016/j.fertnstert.2004.08.030
PMID:15749503
Abstract

OBJECTIVE

To determine whether Thermachoice endometrial ablation (EA) is a safe and acceptable procedure when performed in the outpatient (OP) setting without local anesthesia or IV sedation.

DESIGN

Prospective cohort (double group) study.

SETTING

Hysteroscopy clinic of large UK hospital.

PATIENT(S): Twenty-seven women with menorrhagia.

INTERVENTION(S): The first cohort of women underwent Thermachoice EA without elective analgesia. The second cohort underwent Thermachoice after taking ibuprofen.

MAIN OUTCOME MEASURE(S): To map pain scores and the requirement of "rescue analgesia." To assess speed of recovery and time away from home.

RESULT(S): Thermachoice EA was successfully performed in the OP setting on 89% (n = 24) of women. Four women in the first cohort required rescue analgesia compared to none in the second. During the procedure there was little difference between the groups visual analogue style pain scores-with the overall score being 3.6 (range = 0-10). Postoperatively there was a lower mean pain score in the second cohort, with fewer women experiencing nausea and vomiting. Mean time away from home was 2.6 hours and mean time to make a full recovery was 3.3 days. Women required analgesia for 2.6 days, on average, and returned to their normal activities at this time.

CONCLUSION(S): Thermachoice EA without local analgesia or IV sedation can be safely and successfully performed in the OP setting and if ibuprofen is taken preoperatively few women require "rescue analgesia."

摘要

目的

确定热选择子宫内膜切除术(EA)在门诊环境下不使用局部麻醉或静脉镇静时是否为一种安全且可接受的手术。

设计

前瞻性队列(双组)研究。

地点

英国大型医院的宫腔镜检查诊所。

患者

27名月经过多的女性。

干预措施

第一组女性在未进行选择性镇痛的情况下接受热选择EA。第二组女性在服用布洛芬后接受热选择EA。

主要观察指标

记录疼痛评分及“急救镇痛”的需求情况。评估恢复速度和离家时间。

结果

89%(n = 24)的女性在门诊环境下成功进行了热选择EA。第一组中有4名女性需要急救镇痛,而第二组中无人需要。在手术过程中,两组视觉模拟式疼痛评分差异不大,总体评分为3.6(范围 = 0 - 10)。术后,第二组的平均疼痛评分较低,出现恶心和呕吐的女性较少。平均离家时间为2.6小时,平均完全恢复时间为3.3天。女性平均需要镇痛2.6天,此时恢复正常活动。

结论

不使用局部镇痛或静脉镇静的热选择EA可在门诊环境下安全、成功地进行,并且如果术前服用布洛芬,很少有女性需要“急救镇痛”。

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