Wagner Bernd, Nesslauer Thomas, Bartsch Georg, Hautmann Richard E, Gottfried Hans-Werner
Department of Urology, Universitätsklinikum Ulm, Ulm, Germany.
Ultrasound Med Biol. 2005 Mar;31(3):301-5. doi: 10.1016/j.ultrasmedbio.2004.12.017.
Organ-confined staging for bladder cancer has major impact on further treatment. Most imaging techniques for this purpose are insufficient. We, therefore, assessed the value and the limitations of a new diagnostic tool, the 3-D ultrasound (US) rendering, to distinguish invasive from noninvasive bladder cancers. A total of 63 patients underwent 3-D US of the bladder before transurethral resection or radical cystectomy. The US findings were compared with the pathologic stages of the transurethral resection material or the cystectomy specimens. Superficial (pTa) carcinomas were correctly staged in 66% by 3-D US. Lamina propria infiltrating (pT1) were correctly staged in 83% and the quota of correct staging of infiltrating carcinomas (>pT1) by 3-D rendering was 100%. The overall accuracy was 79%. Three-dimensional US rendering is most valuable to discriminate between superficial stages
膀胱癌的器官局限性分期对后续治疗有重大影响。大多数用于此目的的成像技术都不够充分。因此,我们评估了一种新的诊断工具——三维超声(US)成像,用于区分浸润性和非浸润性膀胱癌的价值及局限性。共有63例患者在经尿道切除术或根治性膀胱切除术前行膀胱三维超声检查。将超声检查结果与经尿道切除材料或膀胱切除标本的病理分期进行比较。三维超声对浅表性(pTa)癌的正确分期率为66%。对固有层浸润性(pT1)癌的正确分期率为83%,三维成像对浸润性癌(>pT1)的正确分期率为100%。总体准确率为79%。三维超声成像对于区分浅表性分期<pT1和肌层浸润性癌>pT1最有价值。这项新技术可能会改善膀胱癌的分期。