Martin C, Auffray J P, Ragni J, Guillen J C, Auge A, Lambert D, Gouin F
Department of Anaesthesia, Sainte Marguerite Hospital, Marseille, France.
Acta Anaesthesiol Scand. 1992 Apr;36(3):226-9. doi: 10.1111/j.1399-6576.1992.tb03454.x.
Gastric contents regurgitation into the oesophagus during induction of anaesthesia may easily fail to be recognized. The incidence of this complication was investigated in 59 consecutive patients. They were scheduled for elective thoracic surgery. Anaesthesia was induced with thiopentone (6 mg.kg-1), fentanyl (3 micrograms.kg-1), and either atracurium (0.4 mg.kg-1), vecuronium (0.1 mg.kg-1) or suxamethonium (1.5 mg.kg-1). Oesophageal pH was monitored with an oesophageal pH probe, connected to a portable computer. The pH probe had a virtually instantaneous response time and was positioned in the lower oesophagus. Acid reflux was defined as a decrease in pH to less than 4.0. During the course of induction, three patients (5%) presented an episode of acid reflux. No patient presented any clinical or radiological signs of pulmonary aspiration. This study suggests that monitoring oesophageal pH is a simple method of detecting gastric reflux during the period of induction.
麻醉诱导期间胃内容物反流至食管可能很容易未被识别。对连续59例患者的这一并发症发生率进行了调查。他们计划接受择期胸外科手术。采用硫喷妥钠(6mg·kg⁻¹)、芬太尼(3μg·kg⁻¹)以及阿曲库铵(0.4mg·kg⁻¹)、维库溴铵(0.1mg·kg⁻¹)或琥珀胆碱(1.5mg·kg⁻¹)诱导麻醉。用连接到便携式计算机的食管pH探头监测食管pH值。该pH探头具有几乎即时的响应时间,置于食管下段。酸反流定义为pH值降至低于4.0。在诱导过程中,3例患者(5%)出现了一次酸反流发作。没有患者出现任何肺部误吸的临床或放射学征象。本研究表明,监测食管pH值是检测诱导期胃反流的一种简单方法。