牛角瓜水提取物对豚鼠气管平滑肌链的体外解痉作用

In vitro spasmolytic effect of aqueous extract of Calotropis procera on Guinea-pig trachea smooth muscle chain.

作者信息

Iwalewa Ezekiel O, Elujoba Anthony A, Bankole Olanrewaju A

机构信息

Department of Pharmacology, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, Nigeria.

出版信息

Fitoterapia. 2005 Mar;76(2):250-3. doi: 10.1016/j.fitote.2004.12.011.

DOI:10.1016/j.fitote.2004.12.011

PMID:15752643

Abstract

The aqueous extract of Calotropis procera was evaluated for its spasmolytic effect using in vitro trachea smooth muscle chain of Guinea-pig. The extract (50, 100 and 200 microg/ml) showed a dose-dependent relaxant activity probably exhibited through the direct relaxant action on the smooth muscle.

摘要

使用豚鼠离体气管平滑肌链评价了牛角瓜的水提取物的解痉作用。该提取物（50、100和200微克/毫升）表现出剂量依赖性的舒张活性，可能是通过对平滑肌的直接舒张作用来实现的。