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Signaling by target of rapamycin proteins in cell growth control.
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2
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Genes Dev. 2003 Aug 1;17(15):1829-34. doi: 10.1101/gad.1110003. Epub 2003 Jul 17.
4
Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase.
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Association of focal adhesion kinase with tuberous sclerosis complex 2 in the regulation of s6 kinase activation and cell growth.
J Biol Chem. 2006 Dec 8;281(49):37321-9. doi: 10.1074/jbc.M605241200. Epub 2006 Oct 16.
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RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
Cell Signal. 2014 Mar;26(3):461-7. doi: 10.1016/j.cellsig.2013.11.035. Epub 2013 Dec 3.
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Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Mol Cell Biol. 2004 Sep;24(18):7965-75. doi: 10.1128/MCB.24.18.7965-7975.2004.

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Metabolic and Mitochondrial Dysregulations in Diabetic Cardiac Complications.
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Effects of Seaweed Polysaccharide on the Growth and Physiological Health of Largemouth Bass, .
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Association of branched-chain amino acids and risk of three urologic cancers: a Mendelian randomization study.
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Structural Insights into the Target of Rapamycin Homolog: A Bioinformatics Approach.
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The uniformity and stability of cellular mass density in mammalian cell culture.
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Proteome changes in an aquatic invertebrate consumer in response to different nutritional stressors.
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本文引用的文献

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Nat Cell Biol. 2004 Nov;6(11):1122-8. doi: 10.1038/ncb1183. Epub 2004 Oct 3.
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Tsc2 is not a critical target of Akt during normal Drosophila development.
Genes Dev. 2004 Oct 15;18(20):2479-84. doi: 10.1101/gad.1240504. Epub 2004 Oct 1.
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Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.
Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13489-94. doi: 10.1073/pnas.0405659101. Epub 2004 Sep 1.
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Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Mol Cell Biol. 2004 Sep;24(18):7965-75. doi: 10.1128/MCB.24.18.7965-7975.2004.
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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.
Nature. 2004 Sep 9;431(7005):200-5. doi: 10.1038/nature02866. Epub 2004 Aug 11.
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The LKB1 tumor suppressor negatively regulates mTOR signaling.
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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells.
Mol Cell Biol. 2004 Aug;24(15):6710-8. doi: 10.1128/MCB.24.15.6710-6718.2004.
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The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.
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