Zhang Shi-Yi, Wang Xin, Zhu Zhi-Hua, Zeng Can-Guang, Rong Tie-Hua, Zheng Lie, Fu Jian-Hua, Xie Ze-Ming, Zhang Xu, Yu Hui
Department of Thoracic Surgery, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, 510060, P.R.China.
Ai Zheng. 2005 Mar;24(3):349-52.
BACKGROUND & OBJECTIVE: Whether to apply routine mediastinoscopy to non-small cell lung cancer (NSCLC) of stage I remains controversial. This study was to evaluate application of cervical mediastinoscopy in detecting mediastinal lymph nodes status of NSCLC of stage I.
The cervical mediastinoscopy was performed in 31 patients with NSCLC of stage I prior to thoracotomy from Oct. 2000 to Feb. 2004. Mediastinoscopy-positive (stage N2) patients received neoadjuvant chemotherapy.
Of the 31 patients, 2 had disease of stage N2, and 1 had disease of stage N3 (right scalenus lymph node metastasis); positive rate of mediastinosopy was 10% (3/31), sensitivity, specificity, and accuracy of mediastinoscopy were 75%, 100%, and 97%, respectively.
Mediastinoscopy might be a routine examination for patients with NSCLC of stage I.
对于Ⅰ期非小细胞肺癌（NSCLC）是否应用常规纵隔镜检查仍存在争议。本研究旨在评估颈部纵隔镜检查在检测Ⅰ期NSCLC纵隔淋巴结状态中的应用。
2000年10月至2004年2月，对31例Ⅰ期NSCLC患者在开胸手术前行颈部纵隔镜检查。纵隔镜检查阳性（N2期）患者接受新辅助化疗。
31例患者中，2例为N2期疾病，1例为N3期疾病（右斜角肌淋巴结转移）；纵隔镜检查阳性率为10%（3/31），纵隔镜检查的敏感性、特异性和准确性分别为75%、100%和97%。
纵隔镜检查可能是Ⅰ期NSCLC患者的常规检查。
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