Robert J, Rochat T, Savioz D, Ludwig C, Spiliopoulos A
Uniteé de chirurgie thoracique, Hôpital cantonal universitaire, Genève.
Schweiz Med Wochenschr. 1998 Jun 6;128(23):895-9.
Retrospective evaluation of conventional mediastinoscopy in the preoperative staging of primary lung cancer.
Between 1978 and March 1997, 117 consecutive patients underwent conventional mediastinoscopy in the preoperative staging of primary lung cancer, after imaging had shown mediastinal lymph nodes larger than 1.5 cm.
In 8 instances no material was found at mediastinoscopy, in 38 the lymph nodes showed no tumorous infiltration, and in 71 the lymph nodes were metastatic. 48 patients underwent thoracotomy in the same stage, with resection achieved in 41. Contraindications for thoracotomy (in 69) were N2 (45) or N3 (11) disease adn/or small cell lung cancer (18). Mediastinal lymphadenectomy was performed in 26 of the 41 patients who underwent lung resection; half of those with negative nodes at mediastinoscopy had in fact N2 disease, with involvement of 2 areas of more in half. There were no deaths due to mediastinoscopy but 4 complications.
A favorable mediastinoscopy is not synonymous with resectable disease, nor does it exclude N2 disease; it does however serve to avoid unnecessary thoracotomies in more than half of cases.
回顾性评估传统纵隔镜检查在原发性肺癌术前分期中的应用。
1978年至1997年3月期间,117例连续患者在影像学显示纵隔淋巴结大于1.5 cm后,接受了传统纵隔镜检查以进行原发性肺癌的术前分期。
8例纵隔镜检查未发现病变,38例淋巴结无肿瘤浸润,71例淋巴结有转移。48例患者在同一阶段接受了开胸手术,其中41例完成了切除。开胸手术的禁忌证(69例)为N2(45例)或N3(11例)疾病和/或小细胞肺癌(18例)。41例接受肺切除的患者中有26例进行了纵隔淋巴结清扫;纵隔镜检查淋巴结阴性的患者中,实际上有一半患有N2疾病,其中一半累及2个或更多区域。纵隔镜检查无死亡病例,但有4例并发症。
纵隔镜检查结果良好并非可切除疾病的同义词,也不能排除N2疾病;然而,它确实有助于在一半以上的病例中避免不必要的开胸手术。