Sikes P J
AACN Clin Issues Crit Care Nurs. 1992 May;3(2):379-91. doi: 10.4037/15597768-1992-2010.
The physiologic and psychologic stress of critical illness produces systemic endocrine responses that affect the body's ability to achieve and maintain homeostasis. Regardless of the nature of the stress or illness, specific hormonal changes occur in thyroid, adrenal, and posterior pituitary activity. This article describes the physiologic and pathophysiologic basis underlying endocrine responses to the stress of critical illness. The critical care nurse is challenged by the complexity of this patient and needs to be familiar with the endocrine responses to critical illness for assessment and clinical interventions to be meaningful.
危重病的生理和心理应激会引发全身内分泌反应，影响身体实现和维持内环境稳定的能力。无论应激或疾病的性质如何，甲状腺、肾上腺和垂体后叶的活动都会发生特定的激素变化。本文描述了危重病应激内分泌反应的生理和病理生理基础。危重症护理护士面临着这类患者病情复杂性的挑战，需要熟悉危重病的内分泌反应，以便评估和临床干预有意义。
