Shah A, Parikh D, Jawaheer G, Gornall P
Department of Paediatric Surgery, Birmingham Children's Hospital NHS Trust, Steelhouse Lane, Birmingham, B4 6NH, UK.
Pediatr Surg Int. 2005 Apr;21(4):270-3. doi: 10.1007/s00383-005-1384-y. Epub 2005 Mar 11.
Persistent rectal prolapse is an uncommon but distressing condition in children. Significant controversy exists regarding its surgical management. The aim of this study was to identify a successful management strategy for persistent rectal prolapse in the paediatric population. Records of all children with rectal prolapse treated surgically at Birmingham Children's Hospital between 1995 and 2003 were retrospectively reviewed. Demographic data, clinical presentation, investigations, treatment modality, complications, and outcome were recorded. Inclusion criteria for the study were failure of conservative management leading to operative treatment. An exclusion criterion was cystic fibrosis. A total of 24 patients with persistent rectal prolapse were identified. Two children with cystic fibrosis were excluded from the analysis. Children below the age of 5 years, group I (n=17), were successfully managed by submucous hypertonic saline injections. Eighty-three percent (14/17) were cured by injection sclerotherapy in this group, 12/14 (71%) requiring one injection and 2/14 requiring a second injection. In the three (17.6%) children in group I in whom sclerotherapy failed, cow's milk protein (CMP) allergy was identified as the causative factor. Children older than 5, group II (n=5), either had behavioural problems (n=3) or were autistic (n=2). This group of children with adult-type, full-thickness rectal prolapse were found to be refractory to initial attempts of injection sclerotherapy. All five children were successfully managed with surgical correction. We conclude that rectal submucous hypertonic saline injections are highly effective for managing early-onset idiopathic childhood rectal prolapse. CMP allergy should be considered in young children with recurrent rectal prolapse. We recommend early definitive corrective surgery in older children with persistent rectal prolapse, as they do not respond to conservative measures or injection sclerotherapy.
持续性直肠脱垂在儿童中虽不常见但令人苦恼。关于其手术治疗存在重大争议。本研究的目的是确定一种针对儿科人群持续性直肠脱垂的成功管理策略。回顾性分析了1995年至2003年间在伯明翰儿童医院接受手术治疗的所有直肠脱垂患儿的记录。记录了人口统计学数据、临床表现、检查、治疗方式、并发症及结果。本研究的纳入标准是保守治疗失败导致手术治疗。排除标准为囊性纤维化。共确定了24例持续性直肠脱垂患者。两名患有囊性纤维化的儿童被排除在分析之外。5岁以下儿童为I组(n = 17),通过黏膜下高渗盐水注射成功治疗。该组83%(14/17)通过注射硬化疗法治愈,其中14例中有12例(71%)只需注射一次,2例需要第二次注射。在I组中硬化疗法失败的3例(17.6%)儿童中,发现牛奶蛋白(CMP)过敏是致病因素。5岁以上儿童为II组(n = 5),其中3例有行为问题,2例患有自闭症。这组患有成人型全层直肠脱垂的儿童被发现对最初的注射硬化疗法尝试无效。所有5例儿童均通过手术矫正成功治疗。我们得出结论,直肠黏膜下高渗盐水注射对于治疗早发性特发性儿童直肠脱垂非常有效。复发性直肠脱垂的幼儿应考虑CMP过敏。对于持续性直肠脱垂的大龄儿童,我们建议早期进行确定性矫正手术,因为他们对保守措施或注射硬化疗法无反应。