Cieslak T J, Robb M L, Drabick C J, Fischer G W
Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814.
Clin Infect Dis. 1992 Apr;14(4):902-7. doi: 10.1093/clinids/14.4.902.
Ochrobactrum anthropi, formerly known as CDC group Vd, is an oxidase-producing, gram-negative, non-lactose-fermenting bacillus that oxidizes glucose and grows readily on MacConkey agar. Only occasionally isolated from human clinical specimens, this organism has rarely been found to be pathogenic. We describe the first reported case of infection due to O. anthropi in a child, that of bacteremia in a 3-year-old girl undergoing chemotherapy for retinoblastoma. In addition, we review the literature concerning cases of infection due to this and closely related bacterial species, namely Alcaligenes xylosoxidans subspecies xylosoxidans, Agrobacterium radiobacter, and "Achromobacter" group B. Finally, we attempt to clarify the confusing history and taxonomy of these organisms as well as make recommendations regarding antimicrobial therapy for infections caused by them.
嗜水气单胞菌,以前称为CDC Vd组,是一种产氧化酶、革兰氏阴性、不发酵乳糖的杆菌,能氧化葡萄糖并易于在麦康凯琼脂上生长。这种微生物仅偶尔从人类临床标本中分离出来,很少被发现具有致病性。我们描述了首例报道的儿童嗜水气单胞菌感染病例,即一名3岁患有视网膜母细胞瘤正在接受化疗的女孩发生的菌血症。此外,我们回顾了有关该菌及密切相关细菌物种(即木糖氧化产碱杆菌木糖氧化亚种、放射形土壤杆菌和“无色杆菌”B组)感染病例的文献。最后,我们试图厘清这些微生物令人困惑的历史和分类,并就它们引起的感染的抗菌治疗提出建议。