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血培养和肺炎的不常见病因:病例报告及文献复习。

; an Unusual Cause of Bacteremia and Pneumonia: A Case Report and a Brief Review of the Literature.

机构信息

HCA Las Palmas/Del Sol Internal Medicine Program, El Paso, Texas, 79902, USA.

出版信息

Infect Disord Drug Targets. 2024;24(4):8-11. doi: 10.2174/0118715265258415231018094653.

DOI:10.2174/0118715265258415231018094653
PMID:38757698
Abstract

Background: Ochrobactrum anthropi spp. is a non-enteric, aerobic gram-negative bacillus that has been reported to cause sepsis and occasionally bacteremia in both immunocompetent and immunocompromised hosts. This bacterium is capable of surviving in various habitats, but due to its affinity for aqueous environments, is hypothesized to have an affinity for indwelling plastic devices and other foreign bodies.

Case Presentation: We report a case of a 66 y/o male with a history of polysubstance abuse disorder admitted for toxic metabolic encephalopathy and found to have bronchopneumonia and bacteremia secondary to infection resulting in sepsis and cardiopulmonary arrest.

Discussion: Ochrobactrum spp. is an unusual pathogen of low virulence and has been noted to cause bacteremia and occasionally sepsis in both immunocompetent and immunosuppressed patients. Isolation of this pathogen in the appropriate setting should be considered a true pathogen and treated as such to avoid sequela of this infection.

Conclusion: This case report and literature review suggest that appears more frequently as a pathogen in nosocomial infections than suggested in the literature.

.
摘要

背景

奥克霍布鲁克氏菌(Ochrobactrum anthropi spp.)是一种非肠道、需氧革兰氏阴性杆菌,已被报道在免疫功能正常和免疫功能低下的宿主中均可引起败血症和偶尔菌血症。这种细菌能够在各种环境中存活,但由于其对水相环境的亲和力,据推测它对留置塑料装置和其他异物有亲和力。

病例介绍

我们报告了一例 66 岁男性,有多种物质滥用障碍病史,因中毒性代谢性脑病入院,并发支气管肺炎和菌血症,继发于感染引起的败血症和心肺骤停。

讨论

奥克霍布鲁克氏菌属是一种毒力较低的罕见病原体,已被报道在免疫功能正常和免疫抑制患者中均可引起菌血症,偶尔引起败血症。在适当的环境中分离出这种病原体应被视为真正的病原体,并应进行治疗,以避免这种感染的后遗症。

结论

本病例报告和文献复习提示,与文献报道相比,奥克霍布鲁克氏菌属在医院获得性感染中作为病原体更为常见。

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