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通过电磁传感器进行非侵入性血糖测量:在静态和动态血液循环中的研究。

Non-invasive glycaemia blood measurements by electromagnetic sensor: study in static and dynamic blood circulation.

作者信息

Gourzi M, Rouane A, Guelaz R, Alavi M S, McHugh M B, Nadi M, Roth P

机构信息

L.I.E.N.; H. POINCARE University, Vandoeuvre Lès Nancy, France.

出版信息

J Med Eng Technol. 2005 Jan-Feb;29(1):22-6. doi: 10.1080/03091900410001720247.

Abstract

In this paper, we present the results of non-invasive blood glycaemia measurements. The blood used in the measurements was calf blood. The measurement method uses an electromagnetic sensor based on eddy currents, which allows the detection of blood glycaemia levels through the variation of the dielectric parameters of the blood. A change in blood glucose concentration causes a variation in the dielectric parameters, in particular conductivity. Detection is only possible at a resonant frequency. The measurements were taken in a static and dynamic state (with and without circulation of blood). The blood is inside a plastic tube placed within the sensor and is surrounded by gelatine, which simulates muscular tissue. The plastic tube simulates the vein where blood circulation occurs. The in vitro results in both cases (static and dynamic) are provided. Under unfavourable conditions we can detect a change of +/- 2 g/l of glucose. We present and discuss these results.

摘要

在本文中,我们展示了无创血糖测量的结果。测量中使用的血液是小牛血液。测量方法采用基于涡电流的电磁传感器,该传感器可通过血液介电参数的变化来检测血糖水平。血糖浓度的变化会导致介电参数发生变化,尤其是电导率。检测只能在共振频率下进行。测量分别在静态和动态状态(血液有无循环)下进行。血液置于放置在传感器内的塑料管中,并被模拟肌肉组织的明胶包围。塑料管模拟血液循环发生的静脉。给出了两种情况(静态和动态)下的体外结果。在不利条件下,我们能够检测到葡萄糖±2 g/l的变化。我们展示并讨论了这些结果。

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