简单测量诊断瞳孔散大的有效性。

Validity of simple measurement to diagnose pupillary dilation.

作者信息

Witting Michael D

机构信息

Division of Emergency Medicine, University of Maryland School of Medicine, Baltimore, 21201, USA.

出版信息

Am J Emerg Med. 2005 Mar;23(2):155-8. doi: 10.1016/j.ajem.2004.03.005.

DOI:10.1016/j.ajem.2004.03.005

PMID:15765335

Abstract

STUDY OBJECTIVE

The aim of the study was to compare the validity of 3 methods of detecting pupillary dilation: bright-light measurement, room-light measurement, and gestalt judgment.

METHODS

In reach volunteer, by random assignment, placebo was instilled in one eye and dilute phenylephrine in the other. Emergency care providers judged whether each pupil was dilated and measured it in bright light (>54,000 lux) and in room light (2700-5400 lux) while the other eye was covered. Test characteristics for measurement were determined according to published cut-points, and measurement methods were compared using receiver operating curve analysis.

RESULTS

There were 136 pupillary assessments-68 in placebo and 68 in phenylephrine eyes. Compared with gestalt judgment, bright-light measurement had higher specificity (0.94 vs 0.68) but lower sensitivity (0.43 vs 0.79). Bright-light measurement was more discriminating than room-light measurement.

CONCLUSION

Bright-light measurement has higher specificity, but lower sensitivity, than gestalt judgement, and is superior to room-light measurement.

摘要

研究目的

本研究旨在比较三种检测瞳孔散大方法的有效性：强光测量、室内光测量和整体判断。

方法

在每位志愿者中，通过随机分配，一只眼睛滴入安慰剂，另一只眼睛滴入稀释的去氧肾上腺素。急诊护理人员判断每个瞳孔是否散大，并在另一只眼睛被遮盖时，在强光（>54,000勒克斯）和室内光（2700 - 5400勒克斯）下进行测量。根据已公布的切点确定测量的检验特征，并使用受试者操作特征曲线分析比较测量方法。