Ahn Andrew, Yang Changhuei, Wax Adam, Popescu Gabriel, Fang-Yen Christopher, Badizadegan Kamran, Dasari Ramachandra R, Feld Michael S
G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Appl Opt. 2005 Mar 1;44(7):1188-90. doi: 10.1364/ao.44.001188.
Harmonic phase-dispersion microscopy (PDM) is a new imaging technique in which contrast is provided by differences in refractive index at two harmonically related wavelengths. We report a new configuration of the harmonic phase-dispersion microscope in a Mach-Zehnder geometry as an instrument for imaging biological samples. Several improvements on the earlier design are demonstrated, including a single-pass configuration and acousto-optic modulators for generating the heterodyne signals without mechanical arm scanning. We demonstrate quantitative phase-dispersion images of test structures and biological samples.
谐波相位色散显微镜（PDM）是一种新的成像技术，其对比度由两个谐波相关波长处的折射率差异提供。我们报告了一种马赫曾德尔几何结构的谐波相位色散显微镜的新配置，作为一种用于对生物样品成像的仪器。展示了在早期设计上的几项改进，包括单通道配置和用于在无需机械臂扫描的情况下生成外差信号的声光调制器。我们展示了测试结构和生物样品的定量相位色散图像。
