Pirog T P, Kovalenko M O
Mikrobiol Z. 2004 Nov-Dec;66(6):80-100.
Author's experimental data and those from literature, concerning the utilization of growth and nongrowth substrates by microorganisms, are presented in the review. The notions "growth" and "nongrowth" substrate as well as the types of transformation of mixed substrates (mixotrophy, diauxia, nongrowth oxidation, cometabolism, syntabolism) have been considered. Main propositions of the conception of auxiliary substrate and the essence of energetic classification of substrates have been presented. Data from literature concerning the effect of cultivation conditions (concentration of substrates, their ratio, cultivation method, dissolution rate under continuous cultivation, etc.) on the character of substrate mixed use, as well as the use of mixed substrates aimed at the intensification of microorganism growth. Data are presented on the intensification of metabolites synthesis (e. g. microbial exopolysaccharide etapolan) on the mixture of energetically non-equivalent growth substrates.
本综述介绍了作者关于微生物利用生长和非生长底物的实验数据以及来自文献的数据。文中讨论了“生长”和“非生长”底物的概念,以及混合底物的转化类型(兼养、二次生长、非生长氧化、共代谢、合成代谢)。介绍了辅助底物概念的主要观点以及底物能量分类的本质。文献中有关培养条件(底物浓度、底物比例、培养方法、连续培养下的溶解速率等)对底物混合利用特性影响的数据,以及旨在强化微生物生长而使用混合底物的数据。还给出了关于在能量不等价的生长底物混合物上强化代谢产物合成(如微生物胞外多糖埃塔波聚糖)的数据。