Huang Yong, Li Dong-jiang, Tang An-wu, Li Qiu-shi, Xia Dong-bin, Xie Ya-ning, Gong Wei, Chen Jing
Department of TCM, Nanfang Medical University, Guangzhou 510515.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 Feb;25(2):119-22.
To observe the effect of scalp acupuncture (SA) on the glucose metabolism in different regions of brain in patients with depression by positron emission computed tomography (PET).
Twelve depressive patients were treated by scalp acupuncture on middle line of vertex (MS5), middle line of forehead (MS1) and bilateral lateral line 1 of forehead (MS2), once a day for six days per week, and received PET detection on different region of brain before and after 6 weeks acupuncture treatment. Semiquantitative analysis was used to compare the average values of radioactive count gotten from various brain regions before and after treatment, which could reflect the condition of glucose metabolism at the brain region detected.
SA could increase the glucose metabolism at bilateral frontal lobes, bilateral parietal lobes, right occipital lobe, right caudate nucleus, right cingulated gyrus and left cerebellum and decrease that at right temporal lobe and bilateral thalamus.
SA on MS5, MS1 and MS2 in depressive patients could influence the glucose metabolism in various brain regions. It primarily illustrated that the mechanism of SA in treating depression is related with its regulation on cortex-limbic circuitry dysfunction and increase the glucose metabolism in various brain regions.
通过正电子发射断层扫描（PET）观察头针疗法对抑郁症患者脑内不同区域葡萄糖代谢的影响。
12例抑郁症患者接受头针治疗，针刺头顶中线（MS5）、额中线（MS1）及双侧额旁1线（MS2），每周6次，每日1次，针刺6周前后进行脑内不同区域的PET检测。采用半定量分析比较治疗前后各脑区放射性计数的平均值，以反映所检测脑区的葡萄糖代谢情况。
头针疗法可增加双侧额叶、双侧顶叶、右侧枕叶、右侧尾状核、右侧扣带回及左侧小脑的葡萄糖代谢，降低右侧颞叶及双侧丘脑的葡萄糖代谢。
对抑郁症患者针刺MS5、MS1及MS2可影响脑内不同区域的葡萄糖代谢。这初步说明头针治疗抑郁症的机制与其调节皮质-边缘系统功能障碍及增加脑内不同区域葡萄糖代谢有关。
