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促性腺激素释放激素在生殖系统疾病中的临床应用。

Clinical applications of gonadotropin-releasing hormones in reproductive disorders.

作者信息

Moghissi K S

机构信息

Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan.

出版信息

Endocrinol Metab Clin North Am. 1992 Mar;21(1):125-40.

PMID:1576979
Abstract

Gonadotropin-releasing hormone (GnRH) agonists show promise as new therapeutic agents with considerable potential for clinical applications in endocrinology, gynecology, pediatrics, and oncology. GnRH agonists are derived from GnRH. This article reviews the physiology and neuroendocrine effects of GnRH and discusses clinical applications of the native substance and its analogs.

摘要

促性腺激素释放激素(GnRH)激动剂有望成为新型治疗药物,在内分泌学、妇科、儿科和肿瘤学等临床应用方面具有巨大潜力。GnRH激动剂由GnRH衍生而来。本文综述了GnRH的生理学和神经内分泌作用,并讨论了该天然物质及其类似物的临床应用。

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