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钝性外伤后出现葡萄膜炎的非霍奇金淋巴瘤。

Non-Hodgkin lymphoma presenting with uveitis occurring after blunt trauma.

作者信息

Soylu Merih, Ozcan Altan Atakan, Okay Okan, Sasmaz Ilgen, Tanyeli Atilla

机构信息

Department of Ophthalmology, Faculty of Medicine, Cukurova University, Adana, Turkey.

出版信息

Pediatr Hematol Oncol. 2005 Jan-Feb;22(1):53-7. doi: 10.1080/08880010590896288.

Abstract

We report here an unusual patient suffering from visual loss with refractory uveitis which was occured after a blunt trauma to her left eye. While in the hospital cervical lymph node and anterior chamber aspiration cytology with immunohistochemical staining were performed. The histopathologic diagnosis was highly malignant B-cell non-Hodgkin lymphoma. After the inflammation of the eye was regressed with chemotherapy, pars plana vitrectomy-lensectomy was performed. She was free of inflammation and the best corrected visual acuity was increased. However, she had a refractory inflammatory episode with clumps of cells in the anterior chamber 10 months after the operation. Local radiotherapy to the left eye was applied. Radiotherapy provided local control and preservation of the vision. The present case is presented in order to emphasize the importance of systemic evaluation in uveitis and possible role of trauma leading migration of atypical cells into the eye.

摘要

我们在此报告一例不同寻常的患者,她因左眼钝挫伤后出现视力丧失及难治性葡萄膜炎。住院期间,进行了颈部淋巴结及前房穿刺细胞学检查并做免疫组化染色。组织病理学诊断为高度恶性B细胞非霍奇金淋巴瘤。眼部炎症经化疗消退后,行玻璃体切割联合晶状体切除术。她的炎症消退,最佳矫正视力提高。然而,术后10个月,她在前房出现细胞团块,发生难治性炎症发作。对左眼进行了局部放疗。放疗实现了局部控制并保留了视力。呈现本病例是为了强调在葡萄膜炎中进行系统评估的重要性以及外伤可能导致非典型细胞迁移至眼内的作用。

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