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[幽门螺杆菌感染与缺血性疾病病情不稳定患者的抗氧化保护状态]

[Helicobacter pylori infection and state of antioxidant protection in patients with the unstable course of ischemic disease].

作者信息

Kratnov A E, Pavlov O N

出版信息

Eksp Klin Gastroenterol. 2004(5):4-9, 145.

PMID:15770853
Abstract

92 patients with ischemic heart disease (IHD) have been examined. Unlike stable angina pectoris, unstable angina and acute myocardial infarction occur more often against the aggravation of chronic atrophic gastritis with a high degree of H. pylori colonization in the mucous coat of the antral part of the stomach. The development of repeated coronary phenomena within one year in patients with unstable angina and acute myocardial infarction was related to the high degree of H. pylori colonization in the mucous coat of the stomach. Irrespective of the presence of IHD in patients, increased H. pylori colonization in the mucous coat was accompanied by a drop in the antioxidant protection activity against the growth of the blood malonic dialdehyde content.

摘要

对92例缺血性心脏病(IHD)患者进行了检查。与稳定型心绞痛不同,不稳定型心绞痛和急性心肌梗死更常发生于慢性萎缩性胃炎加重且胃窦部黏膜幽门螺杆菌高度定植的情况下。不稳定型心绞痛和急性心肌梗死患者在一年内反复出现冠脉现象与胃黏膜幽门螺杆菌高度定植有关。无论患者是否存在IHD,胃黏膜中幽门螺杆菌定植增加均伴随着血液丙二醛含量升高,抗氧化保护活性下降。

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