Mitomo Maki, Miyazaki Chihoko, Mukai Masaya, Usami Yohko, Nagano Shunsuke, Nakamura Noriko, Kubo Kohzoh
Department of Medical Imaging, Sapporo City General Hospital, Japan.
Ann Nucl Med. 2005 Feb;19(1):41-5. doi: 10.1007/BF02986334.
A 27-year-old man developed polymyositis as a manifestation of chronic graft-versus-host disease (GVHD) after non-myeloablative peripheral blood stem cell transplantation (PBSCT). Bone scintigraphy showed intense, striped, and heterogeneous accumulation of Tc-99m methylene diphosphonate (MDP) in the soft-tissue of his lower limbs, while faint activities were seen in the right upper limb. Tc-99m MDP scintigraphy was very useful for accurate and objective evaluation of the severity of the muscle injury and the extent of polymyositis caused by chronic GVHD.
一名27岁男性在非清髓性外周血干细胞移植（PBSCT）后发生了多肌炎，这是慢性移植物抗宿主病（GVHD）的一种表现。骨闪烁显像显示，他双下肢软组织中锝-99m亚甲基二膦酸盐（MDP）呈强烈、条纹状且不均匀的聚集，而右上肢仅见微弱放射性。锝-99m MDP闪烁显像对于准确、客观地评估慢性GVHD所致肌肉损伤的严重程度及多肌炎范围非常有用。
