Susa Antonio, Roveran Antonietta, Bocchi Anna, Carrer Sara, Tartari Stefano
SOC Chirurgia Generale, OC Trecenta, USL 18 Rovigo.
Chir Ital. 2004 Nov-Dec;56(6):817-24.
Intensive rehabilitation programs after major abdominal, thoracic and vascular surgery have been published over the last few years, showing early recovery, fewer complications and a quicker discharge. The aim of the study was to evaluate the feasibility and efficacy of a multimodal intensive rehabilitation program (FastTrack) after major colorectal surgery, according to the experience of Dr. H. Kehlet of Hvidovre University Hospital, Copenhagen. The study design was of the prospective, randomized, controlled type. Forty patients undergoing elective colonic surgery were randomly selected and assigned to two groups well matched for age, weight, ASA and type of resection. The FastTrack group underwent a multimodal rehabilitation program with epidural analgesia, short laparotomy, early feeding and mobilisation. The control group had the usual postoperative treatment with a pain control program. The FastTrack group exhibited a shorter need for assisted ventilation, a lower sedation level and lower opioid consumption over the first 24 hours. We also observed a statistically significant earlier onset of peristalsis (0.5 vs 2.7 days), gastrointestinal function (defecation) (2.8 vs 5.8 days), regular feeding (3.1 vs 7.2 days) and autonomous ambulation (3.3 vs 6.9). The multimodal rehabilitation approach to colon surgery permits an earlier postoperative recovery, better postoperative performance and quicker functional autonomy. These results may have important implications for the management of patients after major colorectal surgery.
在过去几年中,已经发表了关于腹部、胸部和血管大手术后的强化康复计划,这些计划显示出早期恢复、更少的并发症和更快的出院。根据哥本哈根Hvidovre大学医院的H. Kehlet博士的经验,本研究的目的是评估结直肠大手术后多模式强化康复计划(快速康复)的可行性和有效性。研究设计为前瞻性、随机、对照类型。随机选择40例接受择期结肠手术的患者,并将其分为两组,两组在年龄、体重、美国麻醉医师协会分级(ASA)和切除类型方面匹配良好。快速康复组接受了包括硬膜外镇痛、短切口剖腹术、早期进食和活动的多模式康复计划。对照组接受常规术后治疗及疼痛控制方案。快速康复组在最初24小时内辅助通气需求更短及镇静水平更低、阿片类药物消耗量更少。我们还观察到肠蠕动(0.5天对2.7天)、胃肠功能(排便)(2.8天对5.8天)、规律进食(3.1天对7.2天)和自主行走(3.3天对6.9天)在统计学上有显著更早的开始时间。结肠手术的多模式康复方法可使术后恢复更早、术后表现更好且功能自主性恢复更快。这些结果可能对结直肠大手术后患者的管理具有重要意义。