Ponsioen B P, Schuurman W H A Elink, van den Hurk A J P M, van der Poel B N M, Runia E H
Erasmus Medisch Centrum, afd. Huisartsgeneeskunde, Postbus 1738, 3000 DR Rotterdam.
Ned Tijdschr Geneeskd. 2005 Feb 26;149(9):445-8.
In terminally-ill patients in the Netherlands deep sedation by means of a continuous subcutaneous infusion with midazolam occurs more frequently than euthanasia and assisted suicide. Deep terminal sedation is applied to relieve symptoms during the phase of dying, but in contrast to euthanasia and assisted suicide, does not hasten death. In three terminally-ill patients, a 65-year-old man suffering from pulmonary carcinoma, a 94-year-old woman with general malaise, nausea and anorexia, and a 79-year-old woman in the final stage of ovarian carcinoma, a general-practitioner advisor was consulted about an end-of-life decision--deep terminal sedation versus euthanasia or assisted suicide. The first two patients were given deep sedation until death, in both cases a day and a half later. The third patient's request for euthanasia was considered to meet the legal criteria for euthanasia. Compliance with the Dutch statutory criteria for due care in euthanasia and assisted suicide might also be helpful when deciding about terminal deep sedation, but the role and responsibility of the attending physician may differ. However, the radical effects of sedation on the terminally-ill patient and the rapid changes in the clinical situation of the patient when the decision to sedate is taken, both emphasize the need for consultation with another physician.
在荷兰,晚期患者通过皮下持续输注咪达唑仑进行深度镇静的情况比安乐死和协助自杀更为常见。深度终末期镇静用于缓解临终阶段的症状,但与安乐死和协助自杀不同的是,它不会加速死亡。在三名晚期患者中,一名65岁患有肺癌的男性、一名94岁全身不适、恶心和厌食的女性以及一名处于卵巢癌末期的79岁女性,就临终决策——深度终末期镇静与安乐死或协助自杀——咨询了一名全科医生顾问。前两名患者接受了深度镇静直至死亡,两人均在一天半后死亡。第三名患者的安乐死请求被认为符合安乐死的法定标准。在决定进行终末期深度镇静时,遵守荷兰安乐死和协助自杀的法定适当照护标准可能也会有所帮助,但主治医生的角色和责任可能有所不同。然而,镇静对晚期患者的极端影响以及在做出镇静决定时患者临床状况的迅速变化,都强调了与另一位医生进行咨询的必要性。