Aas Pål, Jacobsen Dag
Forsvarets forskningsinstitutt, 2027 Kjeller.
Tidsskr Nor Laegeforen. 2005 Mar 17;125(6):731-5.
The threat from chemical warfare agents such as nerve agents against civilians has traditionally been considered irrelevant. Following the recent terrorist attacks in the US on 11 September 2001 and in Madrid, Spain on 11 March 2004, the threat from such weapons is taken seriously. Hospitals must therefore be prepared to take care of civilian victims. Emergency preparedness implies education and training of healthcare professionals, stocking of antidotes, and training of personnel. This involves decontamination of patients, establishment of routines to avoid contamination of hospitals, and the ability to determine if patients and first responders are contaminated with chemicals and to avoid such contamination. Treatment against nerve agents includes atropine, acetylcholinesterase reactivators (obidoxime or pralidoxime) and benzodiazepines (diazepam). Because these drugs are not sufficiently effective in protecting the brain, new and more effective countermeasures must be developed.
传统上,人们认为诸如神经毒剂之类的化学战剂对平民构成的威胁并不相关。在2001年9月11日美国以及2004年3月11日西班牙马德里发生近期恐怖袭击之后,此类武器构成的威胁受到了重视。因此,医院必须做好照顾平民受害者的准备。应急准备意味着对医护专业人员进行教育和培训、储备解毒剂以及对人员进行培训。这包括对患者进行去污处理、建立避免医院受到污染的常规程序,以及具备确定患者和急救人员是否被化学物质污染并避免此类污染的能力。针对神经毒剂的治疗包括使用阿托品、乙酰胆碱酯酶复活剂(氯解磷定或解磷定)和苯二氮䓬类药物(地西泮)。由于这些药物在保护大脑方面效果不够显著,必须研发新的、更有效的应对措施。