Mbengue M, Seck A, Dia D, Diouf M L, Ka M M, Boye C S, Mboup S, Moreira Diop T
Clinique médicale, Hôpital Aristide Le Dantec de Dakar, BP 6243 Sénégal.
Dakar Med. 2003;48(3):176-80.
Our goals were to describe the epidemiological, clinical and endoscopic aspects of gastrointestinal ulcer and to determine the frequency of H. pylori, we included 140 gastrointestinal peptic ulcers from January 1999 to June 2000. Diagnosis of ulcerous disease delt with the presence of an ulcer discovered during a high digestive endoscopy. Gastro-duodenal ulcers bleeding or with stenosis have been excluded as well as patients who were under anticoagulant treatment or antibiotics or under pump of protons inhibitors during the previous month. Data were collected from a unique questionnaire specifying the sociodemographic characteristic, the history of the ulcerous disease, the antecedents, the style of life, and the endoscopic findings. Five biopsies were done using sterile grips and a fast urease test and the direct exam of the smear. The prevalence of gastro-duodenal ulcers in our population of survey was 6.2%. One hundred twenty eight duodenal ulcers (91.4%), and 12 gastric ulcers (8.6%) were found. The average of age was of 37.1 years +/- 15.3. The sex ratio was 2.9. The gastro-duodenal disease had begun for more than 5 years at 40.8%. No difference in the characters of the pain and signs has been found between duodenal and gastric localization of the ulcer. Hp was associated in 91.4% (91.4% when duodenal ulcers, 88.9% when gastric ulcers and all gastric and duodenal ulcers). We conclude that gastrointestinal ulcers occupies an important place in our gastroenterological practice and the infection rate with H. pylori infection is so high during gastro-duodenal ulcers in our country that the eradication of Hp could be proposed in any case of gastro-duodenal ulcer diagnosed by endoscopy.
我们的目标是描述胃肠道溃疡的流行病学、临床和内镜方面特征,并确定幽门螺杆菌的感染率。我们纳入了1999年1月至2000年6月期间的140例胃肠道消化性溃疡患者。溃疡病的诊断依据是在高分辨率消化内镜检查中发现溃疡。排除了胃十二指肠溃疡出血或伴有狭窄的患者,以及前一个月接受抗凝治疗、抗生素治疗或质子泵抑制剂治疗的患者。通过一份独特的问卷收集数据,该问卷详细说明了社会人口学特征、溃疡病史、既往史、生活方式和内镜检查结果。使用无菌钳取五块活检组织,进行快速尿素酶试验和涂片直接检查。在我们的调查人群中,胃十二指肠溃疡的患病率为6.2%。共发现128例十二指肠溃疡(91.4%)和12例胃溃疡(8.6%)。平均年龄为37.1岁±15.3岁。男女比例为2.9。40.8%的胃十二指肠疾病病程超过5年。十二指肠溃疡和胃溃疡在疼痛特征和体征方面未发现差异。幽门螺杆菌感染率在十二指肠溃疡患者中为91.4%,胃溃疡患者中为88.9%,所有胃和十二指肠溃疡患者中为91.4%。我们得出结论,胃肠道溃疡在我们的胃肠病学实践中占据重要地位,在我国胃十二指肠溃疡患者中幽门螺杆菌感染率很高,因此对于任何经内镜诊断的胃十二指肠溃疡病例,都可以建议根除幽门螺杆菌。