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膀胱颈套叠术可改善前列腺癌根治术后的早期控尿功能:一项前瞻性试验的结果

Intussusception of bladder neck improves early continence after radical prostatectomy: results of a prospective trial.

作者信息

Wille S, Varga Z, von Knobloch R, Hofmann R

机构信息

Department of Urology and Pediatric Urology, Philipps-University Marburg, Marburg/Lahn, Germany.

出版信息

Urology. 2005 Mar;65(3):524-7. doi: 10.1016/j.urology.2004.09.066.

Abstract

OBJECTIVES

To evaluate the impact of intussusception of the bladder neck on post-radical prostatectomy incontinence.

METHODS

A total of 272 men with organ-confined prostate cancer who had undergone radical retropubic prostatectomy were studied. Of the 272 men, 139 underwent bladder neck intussusception and 133 did not. Patients completed validated questionnaires IIQ-7 and a symptom inventory. Continence was defined as the use of no or only one pad daily.

RESULTS

Of the 272 men, 100%, 98.5%, and 96% answered the questionnaire and urinary symptom inventory at baseline and 3 and 12 months postoperatively, respectively. According to the protective pad requirement, 100%, 60%, and 86% of patients without intussusception and 100%, 77%, and 83% of the patients with intussusception were continent at baseline and 3 and 12 months postoperatively, respectively. Univariate logistic regression analysis revealed a statistically significant impact of intussusception on postprostatectomy incontinence at 3 months (P = 0.009), although continence at 12 months did not differ significantly (P = 0.5).

CONCLUSIONS

Intussusception of the bladder neck had a significant effect on regaining continence at 3 months, although continence at 12 months was not affected.

摘要

目的

评估膀胱颈套叠对根治性前列腺切除术后尿失禁的影响。

方法

对272例接受根治性耻骨后前列腺切除术的局限性前列腺癌男性患者进行研究。在这272例男性患者中,139例发生膀胱颈套叠,133例未发生。患者完成了经过验证的IIQ-7问卷和症状清单。尿失禁的定义为每天使用不超过一片或仅一片尿垫。

结果

在272例男性患者中,分别有100%、98.5%和96%在基线时以及术后3个月和12个月时回答了问卷和泌尿系统症状清单。根据尿垫使用需求,在基线时、术后3个月和12个月时,未发生膀胱颈套叠的患者分别有100%、60%和86%实现控尿,发生膀胱颈套叠的患者分别有100%、77%和83%实现控尿。单因素逻辑回归分析显示,膀胱颈套叠对术后3个月的尿失禁有统计学上的显著影响(P = 0.009),尽管术后12个月时的控尿情况差异不显著(P = 0.5)。

结论

膀胱颈套叠对术后3个月恢复控尿有显著影响,尽管术后12个月时的控尿情况未受影响。

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